Publications
[Phytoestrogens in menopausal women: a review of recent findings].
- Publication date : 2003-11-12
Reference
Dodin S, Blanchet C, Marc I. [Phytoestrogens in menopausal women: a review of recent findings]. Med Sci (Paris). 2003;19:1030-7. doi: 10.1051/medsci/200319101030. PubMed PMID: 14613019.
Additional information
Keywords
aged bone density breast neoplasms cardiovascular diseases case-control studies clinical trials as topic female hormone replacement therapy humans isoflavones lipids menopause middle aged osteoporosis phytoestrogens plant preparations risk factors
Abstract
Many women seek alternatives to hormone replacement therapy (HRT). Phytoestrogens are nonsteroidal compounds with estrogenic or antiestrogenic properties. Six of the 16 clinical trials suggest a significant reduction in alleviating symptoms but to a lesser degree than HRT. A meta-analysis showed that phytoestrogens improve lipid profile. The 14 recent clinical trials led, however, to divergent findings. Small clinical trials suggested a protective effect of phytoestrogens on bone metabolism. High concentration of phytoestrogens was associated with a reduction in breast cancer risk in case-control studies.
